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Description
Mice also received 100 mg/kg of L-Carnitine once a day for 5 days

Acetyl L-Carnitine (ALCAR) is a modified amino acid that supports cognitive health, brain function, and energy production

Gamma-butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of l-carnitine to TMAO

The carnitine biosynthesis pathway (Vaz et al., 2002) (A) The chemical structures of the five carnitine biosynthesis metabolites

Chemico-Biological Interact

In these studies, it was reported that high TMAO levels trigger 34-36 and exacerbate 37 vascular inflammation with proinflammatory effects, cause endothelial damage, 34 inhibit reverse cholesterol transport, 19 and increase the transformation of macrophages into foam cells 38 as well as platelet activation and thrombosis formation
