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They contribute significantly to tissue repair and immune regulation [64, 65] by coordinating immune and inflammatory processes through phagocytosis, ROS generation, degranulation, cytokine and chemokine production, and the release of neutrophil extracellular traps (NETs) [66,67,68,69]

In a different study, ZEA activated the PKC, ERK, and p38 MAPK signaling pathways in pig pituitary cells to decrease the production of (follicle-stimulating hormone) FSH by GPR30 (G-protein-coupled receptor) (89)

[DOI] [PMC free article] [PubMed] [Google Scholar] 241.Bossong M, Wilson R, Appiah-Kusi E, Linsen F, Zelaya F, Allen P, et al