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These studies will be critical for understanding the research utility of this pathway and identifying optimal applications for future investigational development

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J Clin Oncol 20 : 19231931 Estlin EJ, Pinkerton CR, Lewis IJ, Lashford L, McDowell H, Morland B, Kohler J, Newell DR, Boddy AV, Taylor GA, Price L, Ablett S, Hobson R, Pitsiladis M, Brampton M, Clendeninn N, Johnston A, Pearson AD (2001) A phase I study of nolatrexed dihydrochloride in children with advanced cancer

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