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Isomalt may prove upsetting to the intestinal tract because it is incompletely absorbed in the small intestine, and when polyols pass into the large intestine, they can cause osmotically induced diarrhea and stimulate the gut flora, causing flatulence

Peptides are less immunogenic and have pharmacokinetic advantages similar to those of sdAbs, with excellent uptake in tumor tissue and rapid clearance [97]

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Both caffeine and nicotine are stimulants that stimulate sympathetic nervous system arousal