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doi: 10.3727/096368910X508906

Because it degrades in blood in a pathway involving amino-peptidases, it may not be suitable for people who take medications that inhibit or are metabolized by peptidases (e.g., captopril, a treatment for hypertension).4 Also, based on what we know about other therapeutic peptides, we would say DSIP is contraindicated for women who are pregnant or breastfeeding as well as people with a personal history of cancer

[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Cortes-Santiago N., Hossain M.B., Gabrusiewicz K., Fan X., Gumin J., Marini F.C., Alonso M.M., Lang F., Yung W.K., Fueyo J., et al

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DSIP is discussed as a signaling peptide that may affect sleep timing and the stress response
