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Of the 275 randomized participants (placebo, n = 138

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For example, excessive alcohol consumption promotes the translocation of intestinal -glucan to the liver, where it binds to Dectin-1 on liver macrophages, activating the NLRP3 inflammasome and contributing to the development of alcoholic hepatitis (Wu et al., 2020b)

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Nevertheless, the detailed mechanisms of diabetic osteoporosis remain unclear