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Lipoprotein-associated phospholipase A2 (Lp-PLA2) and autotaxin, enzymes present on Lp(a), are also likely to be involved in the pathogenesis of AVS/CVD [32]

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Guinea pigs possess a highly mutated gene for L-gulono-gamma-lactone oxidase, the key enzyme for L-ascorbic acid biosynthesis missing in this species

Research on the melanization process and the role of phenoloxidase in insect physiology, including immune response, has been conducted in species belonging to different orders, e.g., Blattodea ( Periplaneta americana ), Coleoptera ( Tenebrio molitor and Tribolium castaneum ), Diptera ( Anopheles gambiae , Drosophila melanogaster , and Musca domestica ), Hemiptera ( Acyrthosiphon pisum ), Hymenoptera ( Apis mellifera and Bombus terrestris ), Lepidoptera ( Bombyx mori , Galleria mellonella , Hyalophora cecropia , and Manduca sexta ), Odonata ( Argia anceps ), and Orthoptera ( Acheta domesticus and Locusta migratoria ) [31]

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