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The evidence that hypotaurine, through its binding to soluble A, reduces the production and aggregation of oligomers, as well as its ability to lessen the toxicity of -amyloid (A) in primary cultured neurons and amyloid plaques in a mouse model, provides support for this assertion (129)

An open-label biomarker study of EMA401 was conducted in a phase II clinical trial of OIPN patients to prove the conceptual use of EMA401 in OIPN

doi: 10.1016/j.kisu.2020.12.002 250

Changes in Gene Expression Following treatment of Adverse Risk Acute Myeloid Leukemia

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