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This study is the first to describe the role of ferroptosis in fat graft survival and demonstrate the potential of this pathway as a therapeutic target for improving lipotransfer success

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Under normoxic conditions, HIF-1 is hydroxylated by the prolyl hydroxylase domain protein 2 (PHD2), and then it interacts with the von Hippel Lindau protein (VHL)
The cells of the prostate produce high levels of polyamines and inhibition of polyamine synthesis is effective at suppressing tumor growth in prostate cancer [91]

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