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Genomics 80 , 433442 (2002)

Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H 2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years

The IL-33 model was specifically selected to isolate ILC2-intrinsic responses independent of upstream epithelial-derived alarmin complexity present in the previously employed Alternaria model ( Figure 1 )

Indeed, enhanced levels of oxidant species within a cell can lead to permanent cellular damage and contribute to cell death (Redza-Dutordoir and Averill-Bates, 2016)

Furthermore, PET imaging in a disseminated mouse model demonstrated tumor cell localization in femur, tibia and spine, highlighting the potential of this antibody-based PET radiopharmaceutical for non-invasive CD38-positive myeloma imaging [101]