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It was located in association with the inner membrane toward the cytoplasmic side, suggesting easy accessibility to extracellular peptides (Takahashi and Watanabe, 2004)
Recent research has shown that rhein can alleviate changes in the renal microstructure of model rats, and decrease the expression of apoptosis-related proteins, thereby reducing cell apoptosis, and counteracting the damage caused by oxidative stress to the kidneys (184)
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Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance
Curcumin attenuates thermal hyperalgesia in a diabetic mouse model of neuropathic pain
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