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Maintenance dosing schedules: Weekly injections for the first few months Bi-weekly or monthly injections after that Adjusting Frequency Based on Clinical Response The B12 injection schedule might need to change based on how well the treatment works

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doi: 10.1093/jnci/85.18.1492 160 QiaoYLDawseySMKamangarFFanJHAbnetCCSunXDet al

The constructed pURA3-GSH1 strain was heterozygous at the GSH1 locus, with one allele expressing the URA3 ORF under pGSH1 control and the other expressing GSH1 under pTEF1 control (FigureS1 A )

7987 Table 1