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Zinc oxide nanoparticles attenuate hepatic steatosis development in high-fat-diet fed mice through activated AMPK signaling axis

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Summary: Antioxidants may help fatty liver disease by reducing oxidative stress, but current NHS and NICE guidance recommends lifestyle modification as first-line treatment, with vitamin E considered only for specific adults with biopsy-proven NASH under specialist supervision

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An increase in necrotic cells was also observed across all treatments with most produced by CLB treatment in HT29 cells

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