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It points out that many human trials have used very small sample sizes, usually between 17 and 80 people, which restricts the findings statistical power and potential to be applied to larger groups

This nanomedicine not only effectively inhibits tumor growth with fewer side effects, but also significantly inhibits lung metastasis by blocking the HMGB1-TLR4 axis [249]

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This patient's primary issue is a lack of central dopamine causing motor freezing, and inhibiting its conversion to norepinephrine would not alleviate these extrapyramidal symptoms

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