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It facilitates the resolution of inflammation through NF-B deacetylation and by activating AMPK, PGC-1, and PPAR-1However, SIRT1 activity is reduced by NF-B via the expression of miR-34a, IFN, and ROS, which causes inflammatory reactions that have been linked to a number of chronic metabolic and related diseases (Kauppinen et al., 2013)

All these carriers have their unique properties depending on the structure and hence appropriate for different therapy applications

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