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The MHRA states that low vitamin B12 is now considered to be a common side effect, especially when taking high-dose or long-term metformin, affecting up to one in 10 people

doi: 10.1016/j.freeradbiomed.2008.10.050

PMID: 61 MoreiraX.Abdala-RobertsL.CubasJ.Lago-NezB.et al

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