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[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Liu H, Deng Y, Wu L, Li Y, Lin N, Li W, et al
Research on LL29 (IPF lung fibroblasts), NHLF (normal lung fibroblasts), and DHLF (diseased lung fibroblasts) cells showed that biochanin-A increased Smad7 expression and decreased Smad2 mRNA expression, indicating inactivation of the TGF-/Smad signaling pathway [129]
In this review, we highlight insights from recent unbiased phosphoproteomics studies, which have enabled a comprehensive examination of insulin signalling and have transformed our perspective on how signalling changes may contribute to insulin resistance
Editors HeissigW.MllerC
A recent phase II clinical trial has confirmed that treatment of pamrevlumab, which is a fully human recombinant monoclonal antibody against CTGF, can significantly reduce the decline of FVC and attenuate the progression of IPF
In addition to MTHFR polymorphism, studies examining effect of polymorphisms in other FOCM genes and risk of PD are very limited
