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Description
While IGF-1 LR3 was engineered for extended half-life and systemic activity, IGF-1 DES follows the opposite strategy: very short half-life (20-30 minutes) but extreme potency at the site of injection

Statements Author contributions CF and NB-V wrote the initial draft

(2) Patients with major heart, liver, kidney, and other organ disorders, including co-infection with hepatitis C virus (HCV), hepatitis D virus (HDV), or other chronic liver diseases such as alcoholic liver disease, non-alcoholic fatty liver disease (NAFLD), and autoimmune hepatitis

doi: 10.1038/s41577-024-01027-3 103 SeokJKKangHCCho-YLeeHSLeeJY

With the test concentration up to 200 nM, CdSe@ZnS-GSH QDs show high biocompatibility to cells and do not affect cell proliferation, disturb cell membrane integrity or cause apoptosis and necrosis of cells

So in theory, both support muscle growth and hypertrophy while shortening the time for muscle recovery following intense physical activity
