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It is, therefore, reasonable to suggest that exosomal miRNAs in peripheral blood may vary across different diseases

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Ferroptosis-inducing factors can directly or indirectly affect the imbalance of oxidative stress and antioxidant system through different ways, such as inhibiting glutathione synthesis, inactivating glutathione peroxidase 4 (GPX4), accumulating lipid reactive oxygen species (ROS), and finally leading to cell death (Cao and Dixon, 2016)

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doi: 10.1097/MAO.0000000000000466

doi: 10.1128/CVI.00068-08 326 Stucky HunterERichardsonMDDenningDW