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Sulfur metabolism pathways, particularly cysteine metabolism, were examined, including methylation, trans-sulfuration of homocysteine to cystathionine, and cysteine catabolism (Fig

GPX4 converts the reduced form of GSH into oxidized glutathione (GSSG) and promotes the reduction reaction from lipid peroxides (LOOH) to corresponding alcohols (LOH) (Li F

Vision loss deterioration of the eye lens, which contributes to blindness

however, in some extracellular spaces such as the lining fluid of the lung, a thin layer of fluid covering the air spaces where gas exchange occurs, there is high concentration of GSH that is secreted by epithelial cells (Sutherland et al., 1985

Mistry V

Acknowledgements We would like to thank the VIB Bioimaging Core and IRC Immunohistochemistry services (K
