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, 2019 ,doi: 10.1007/s10157-019-01727-4

Discussion N -acetylcysteine appears to be promising in the treatment of several psychiatric disorders

PXN inhibits phosphodiesterase 9 (PDE9), which terminates nitric oxide (NO) neurotransmission by metabolizing cyclic guanosine monophosphate (cGMP) back to GMP

The FEBS Journal

437 Lipid droplet accumulation was observed in brown adipose tissue and heart in a mouse model of Friedreichs ataxia, as well as in Frataxin-deficient rat cardiomyocytes and IPSC-derived cardiomyocytes

cGAS can be activated by any dsDNA in a sequence independent manner to activate cGAS-STING signaling pathway, which has been reported to be a critical pathway for anti-tumor, antiviral and anti-bacterial defense (53, 103)