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The literature was monitored as the manuscript was developed, and papers identified reviewed for relevance

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For example, sulforaphane significantly decreased microglial cell viability at 50 M (Eren et al., 2018)

Moreover, Electrospinning produces ultra-fine nanofibers which can encapsulate nutraceutical compounds within or between polymer strands

if it does not occur, chronic wounds develop that are slow to close [2, 3]

In the same way, pejorative endpoint such as treatment failure, or negative long-term outcomes such as hospitalization or even colectomy will be prompter to occur among patients starting with less effective first-line advance therapy