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Generally, after 812 weeks of continuous use, a 4-week washout period is required to avoid tolerance from long-term continuous use

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For histone H2b, Epitalon bound at site 3 near the N-terminal alpha helix, formed 12 docking solutions and binding via the sequence Val-Glu-Thr-Ser-Asn-Ser-Asn with an energy of 23.10 kcal/mol

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