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doi: 10.1158/1535-7163.MCT-13-0208 227 PraharajMShenFLeeAJZhaoLNirschlTRTheodrosDet al

Serum homocysteine and dementia: Meta-analysis of eight cohort studies including 8669 participants

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Protection Of Mitochondrial Proteins And DNA Inhibition of Protein Oxidation:ROS can oxidize mitochondrial proteins, leading to loss of function

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Regardless of the underlying molecular mechanism, most pathogenic variants yield substantially decreased or null activity of CBS
