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In human stimulant users, both the presynaptic and postsynaptic functions of the dopamine system in the striatum are downregulated 2,3,4

These results are supported by El-Sherbini et al

Ischemia-reperfusion injury The heart muscle may become oxygen-deprived (ischemic) as the result of myocardial infarction or during cardiac surgery

& Davies, S
Biochim Biophys Acta (2016) 1861:56683
