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The high metabolic demands of stria vascularis, sensory hair cells, and spiral ganglion neurons (SGNs) render these structures susceptible to the detrimental effects of ROS

Several physical, chemical, and biological techniques, as well as different approaches to breeding and genetic engineering, have been employed to diminish the toxicity of aflatoxin and lower its level below the required one in order to minimise its contamination in agricultural plants [100]

The simultaneous interaction with the endogenous Ub-E2-E3 complex and the protein of interest results in the generation of an Ub-E2-E3-neosubstrate complex, ultimately leading to ubiquitinylation and degradation of target protein

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10.2337/db23-0498 [DOI] [PMC free article] [PubMed] [Google Scholar] 20.Sokolowski EK, Kursawe R, Selvam V et al (2024) Multi-omic human pancreatic islet endoplasmic reticulum and cytokine stress response mapping provides type 2 diabetes genetic insights

Korsmo HW, Jiang X