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The inclusion of glutathione helps to reduce the appearance of dark spots and hyperpigmentation, while niacinamide works to strengthen the skin barrier and provide long-term brightening effects

Journal of Hematology and Oncology , 15 ( 1 ), 83

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Moreover, the PHO pathway is intricately regulated at both the transcriptional and post-transcriptional levels, with key regulatory factors such as PHO2 and miRNAs (Prathap et al., 2022)

Individual results may vary based on factors such as age, baseline skin condition, dosage, and whether astaxanthin is used orally, topically, or both

Under the low-glucose concentration (0.5%), resveratrol supplementation did not affect the CLS of the yap1 strain ( Fig