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It usually begins between the ages of 50 and 70 and is slightly more common in men than women, with a male-to-female ratio of about 1.51 (Renton et al., 2011)

Intlim: integration using linear models of metabolomics and gene expression data

doi: 10.1093/ndt/gfq580 64

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Excessive mtROS production from the ETC is linked to the hyperglycemic damage seen in diabetes [16,31]
