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Maurer B, Singh D, Martinez F, Newman K
10.1038/s41467-022-31306-3
Commun., 12 : 3985
Gillespie ZE, Pickering J, Eskiw CH (2016) Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
The three mRNAs differ in their 5 ends but share 12 common exons (exons 2-13), six of which encode the PFK-2 catalytic domain and six of which encode the F-2,6-BPase catalytic domain
However, the fate of GAB depends on ABAT, that is, GAB is diverted into the tricarboxylic acid (TCA) cycle in the presence of ABAT in T H 17 cells instead of being exported into the extracellular compartment in the absence of ABAT as in iT reg cells
