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Gene expression analysis in peripheral memory T cells then revealed a clear PD-specific gene signature with transcriptomic markers for inflammation, oxidative stress, phosphorylation, autophagy of mitochondria, cholesterol metabolism, and chemokine signaling via CX3CR1, CCR5, and CCR1

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Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I

Although testosterone (T) administration can increase insulin-like growth factor-I (IGF-I) when administered to hypogonadal men, no studies have examined whether this occurs in normal men