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Patients should inspect injection sites for signs of infection, unusual swelling, or persistent nodules, which should prompt clinical evaluation

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En condiciones normales la l-carnitina se produce de forma endgena principalmente en el hgado de los animales, a partir de los aminocidos lisina y metionina, a travs de varias reacciones metablicas que requieren adems vitamina B 6 , vitamina C y hierro

Many patients who take colchicine for an extended period of time experience gastrointestinal problems and must discontinue the medication

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12 In addition, there is an unusually high frequency of homozygosity for mutations in the SLC22A5 gene in families of patients with primary carnitine deficiency and no known consanguinity, 6,9,1214 including a new patient (Patient 268) reported in this study