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Intravenous (IV) glutathione is limited by an extremely short half-life in the plasma, and it cannot cross cell membranes intact, but must be broken down and resynthesized within the cell

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With mimicking neutrophil, the nanoparticles with intratracheal injection actively penetrate the mucus and arrive at the inflammatory sites, escape macrophage clearance and prolong the retention in the lungs, eliminate the bacteria by LVX and neutralize cytokines by the neutrophil membrane, achieving therapeutic efficiency in bacteriainfected COPD

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Lu TY, He Y, Ai YM, Lu T, Ai Y et al (2025) Effects of seleniumcadmium interactions on soil cadmium forms and the enrichment of selenium and cadmium in rice