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A dose of pure R-lipoic acid provides twice the active ingredient compared with typical alpha-lipoic acid supplements, simply because the whole dose consists of the active R molecule

2014 (PMID 25187433), which tied the procognitive effect to HGF/c-Met dependence, was retracted in 2025 (retraction notice PMID 40312093)

This made me wonder about the unexplained nausea I experienced two days ago (didnt vomit but it was close), which Im still noticing (though less acutely), and the great fatigue which accompanied it

[DOI] [PMC free article] [PubMed] [Google Scholar] 63.Meijnikman AS, Davids M, Herrema H, Aydin O, Tremaroli V, Rios-Morales M, Levels H, Bruin S, de Brauw M, Verheij J, et al