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Human data are limited

Peter Attia, a longevity physician, discusses NAD+ precursors: "While evidence is emerging, NAD+ boosting shows promise for mitochondrial health and longevity, though IV might not be optimalprecursors like NMN could be better."[33][20] On combinations, he cautions on long-term data but notes potential for metabolic disorders

Safety data is limited to the preclinical studies, where no adverse events were reported at therapeutic doses during the 11-week treatment period the longest published study duration

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