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All had adequate vitamin B 12 intake and were well nourished

Visceral fat is metabolically active and strongly linked with insulin resistance, heart disease, and metabolic syndrome

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Ninomiya JK, LItalien G, Criqui MH, Whyte JL, Gamst A, Chen RS

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The investigators reported that oral AOD-9604 administration in rodent models produced measurable increases in fat oxidation and reductions in body fat, and that direct application of the compound to ex vivo human adipose tissue produced concentration-dependent increases in lipolysis [2]