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Timing & Dosage Considerations Split Dosing: Many protocols divide the daily dose into two or three smaller administrations to maintain steady blood levels

The following substances, and other substances with similar chemical structure or similar biological effect(s), are prohibited: S2.1

Effect of estrogen upon cyclic ADP ribose metabolism: beta-estradiol stimulates ADP ribosyl cyclase in rat uterus

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Striking the right balance is not merely a matter of convenience
