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unc1 animals show altered fat metabolism and ablation of nhr1 restores their lipid profile To further investigate the altered lipid metabolism associated with unc1 mutants, we analysed their lipid content using Oil Red O

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Furthermore, oligofructose promotes satiety and reduces plasma TG in rats fed a high-fat diet by up-regulating the level of GLP-1 in the gut (Cani et al., 2005)