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Considering that the dialysate carnitine content before and after hemodialysis is far below that of control subjects and that the loss of carnitine into the dialysate greatly exceeds that into urine, the net loss of carnitine is mostly attributed to dialysis procedures [81, 82]

Pioglitazone improves mitochondrial function in the remnant kidney and protects against renal fibrosis in 5/6 nephrectomized rats

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There was a significant reduction (about 60%) in plasma TMA and TMAO during a single hemodialysis session and the post-dialysis levels were not significantly different from that in control subjects