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Our previous studies have also shown that the improvement effect of ketogenic diet on MASLD is related to the livers ketogenic capacity, plasma -OHB levels peaked at 2 weeks after KD feeding, then decreased at 0.8 mmol/L after 6 weeks of KD feeding, which are consistent with the blood biochemical indexes (blood lipids, AST, ALT and etc.) and liver morphological changes in MASLD mice [26]