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Some supplements, such as multivitamins or vitamin B12 tablets, also contain vitamin B12
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In one human study, female participants who applied a topical cream containing all five growth factors daily for four weeks experienced the following: 4 Decreased wrinkles under the eyes by 46% Reduced appearance of crow's feet by 21% Increased skin elasticity by 47% Enhanced skin hydration by 64% (improved by 83% immediately after applying) Accelerate Epidermal Regeneration Epidermal stem cells are responsible for self-renewing the skin's surface
NCT06376591)

PMID: 7766968

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