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While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

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[DOI] [PMC free article] [PubMed] [Google Scholar] 181.Langin D, Arner P

In addition, improvements address stormwater run-off and hydraulic restrictions at the plant to prevent backups and overflows to the wastewater system during storm events