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Improved hepatic insulin sensitivity normalises sex hormone binding globulin (SHBG) production, which in turn lowers free androgens

it also evokes beneficial effects in lowering the incidence of metabolic disorders related with aging, overweight or obesity, insulin resistance, and cardiovascular disease [19]

The lower 5-GABA A receptor levels we observe may therefore contribute to reductions in tonic inhibition, leading to an increase in hippocampal hyperexcitability

To ensure clarity, the focus of this discussion is primarily on autism and its association with folate receptor autoantibodies, while acknowledging that other neurological disorders, such as epilepsy and Parkinsons disease, may have related metabolic issues but are not necessarily linked directly to folate autoimmunity

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