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It appeared that the patient was a poor metabolizer of CYP2D6 , the most important phase I enzyme to metabolize venlafaxine

Recent Advances: Reductive stress broadens our view of the importance of cellular redox homeostasis and the influences of an imbalanced redox niche on biological functions, including cell metabolism

Causal association of diet-derived circulating antioxidants with the risk of rheumatoid arthritis: A Mendelian randomization study

Wang Y, Yuan J, Han Z

Collectively, these data suggest that OspC-mediated ADP-riboxanation of SEPT9 at Arg561 impairs salt bridges and disrupts the SEPT9-SEPT9 NC-interface, thereby preventing septin recruitment and S