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ii) neurosecretory granules can be observed under an electron microscope, and iii) the catecholamine metabolite VMA level increases in the urine

Examples of such medications include the following 154,164 : Gabapentin (Neurontin), an anti-seizure drug Fluoxetine (Prozac), citalopram (Celexa), escitalopram (Lexapro), and paroxetine (Paxil), antidepressants in the selective serotonin reuptake inhibitor (SSRI) class Memantine (Namenda), an N-methyl-D-aspartate (NMDA) receptor antagonist Sodium oxybate (Xyrem), an anti-anxiety and sedative Tramadol (Ultram), an opioid pain reliever and SNRI Although over-the-counter analgesics and anti-inflammatory drugs, such as acetaminophen (Tylenol), ibuprofen (Advil), and naproxen (Aleve), are frequently used, these medications have not demonstrated efficacy for reducing fibromyalgia pain in clinical trials

Also reviewed by David C

Data Availability Protocols used are specified or referenced in the manuscript

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