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Although glutamine production happens primarily by active skeletal muscle, intense muscle contraction increases the demand for glutamine, which competes for the same fuel nutrient as lymphocytes and macrophages, forcing a modulation of these cells in favor of the musculature (Newsholme, 1994)

Be patient, as not all fat will survive, and final results may take a few months to appear

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doi: 10.20892/j.issn.2095-3941.2020.0219 226 BlancafortAGir-PerafitaAOliverasGPalomerasSTurradoCCampuzanoet al

In addition, alternative delivery strategiesincluding nose-to-brain nanoparticle systems and nanoparticles exploiting receptor-mediated and adsorptive-mediated transcytosis, as well as synaptic dysfunction targetingare discussed