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Possible Causes of Vitiligo The primary causes behind vitiligo development include several interconnected mechanisms: Autoimmune response : In some people, the immune system wrongly identifies pigment-producing cells (melanocytes) as harmful and destroys them

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2 The global burden of IHD: incidence, prevalence, and mortality Cardiovascular diseases account for 32% of all global deaths, with an estimated 19.8 million deaths annually, and 85% of these deaths are attributed to IHD and stroke (WHO, 2017)