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doi: 10.1152/ajpendo.00287.2009
& Andreucci, A

An imbalance in total antioxidant levels in the serum of women with PCOS can exacerbate cell damage and reduce cellular defense ability (119)
Taken orally, glutathione has inherently low bioavailability as it faces two key obstacles: the strong acidity of gastric juices and the action of a liver enzyme called gamma-glutamyltranspeptidase (GGT) which catalyzes the first stage of its breakdown (8)