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O.di SummaP

Metabolic activation of mitochondria in glioma stem cells promotes cancer development through a reactive oxygen species-mediated mechanism
To better understand the transcriptional mechanisms, we performed ATAC sequencing to assess chromatin landscape changes occurring upon Nrf2 loss-of-function
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reported that upregulated transsulfuration pathway for cysteine synthesis in erastin-resistant ovarian cancer cells compensates for cysteine deprivation by xCT blockage, which is mediated by Nrf2-mediated CBS activation (51)

10.1002/jbmr.7 11 ChenJ
