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Oxidants in Biology

In addition, the ratios of some ions (e.g., sodium and chloride) may be important for maintaining plasma, nuclear, and mitochondrial membrane integrity

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Injection technique and local adverse reactions

A recent study has indicated that overdose (intraperitoneal dose of 800 mg/kg body weight) of NAC causes organ dysfunction, fatty liver, renal tubular necrosis, splenic damage, and even death in mice (Tsai et al., 2024)

We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig