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The primary safety endpoints are the proportion of patients with any treatment-emergent adverse events (TEAEs) related to study RBC transfusion through 28 days, and the proportion of patients with treatment-emergent antibodies with confirmed specificity to pathogen-reduced RBCs through 75 days after the last study transfusion

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The structure of the E-domains has not been resolved, and their molecular functions are still unclear

The exact binding capacity will depend on a number of parameters including binding buffer and the size of the GST-fusion protein